Physicians - Lawrence K. Gates, Jr., M.D., F.A.C.P., F.A.C.G., A.G.A.F.

Board Certified Internal Medicine, Board Certified Gastroenterology, Board Certified Nutrition Support

 

Dr. Gates graduated from Duke University School of Medicine, where he completed his Internal Medicine internship and residency. He completed a Gastroenterology fellowship at the Mayo Clinic, and was an Associate Professor at the University of Kentucky.


Current Position
- 2002 – Present | Specialist in Gastroenterology, Salem Gastroenterology Consultants, Salem, Oregon. Practice includes special interest in acute and chronic pancreatitis, gastrointestinal endocrinology, inflammatory bowel disease, and therapeutic endoscopy.
Education
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1982 | College, Utah State University, Logan, Utah B.S. in Biology, magna cum laude

- 1982 – 1986 | Medical School, Duke University School of Medicine Durham, North Carolina
- 1986 – 1989 | Internship and Residency, Duke University School of Medicine, Durham, North Carolina
- 1989 - 1993 || Research Fellow, Mayo Clinic, Rochester, Minnesota
Professional Experience
- 1993 -1999 | Assistant Professor of Internal Medicine, University of Kentucky
- 1999 - 2002 | Associate Professor, Internal Medicine, University of Kentucky
- 1997 – 2002 | Director, Pancreatic Disease Service, University of Kentucky
- 1998 – 2000 | Associate Member, Graduate Faculty, Nutritional Sciences Program, University of Kentucky
- 2000 – 2002 |Associate Professor, Graduate Center for Nutritional Sciences,University of Kentucky
- 2000 – 2002 | Gastroenterology Section Chief, Lexington VA Medical Center
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2002 - Present | Gastroenterologist, Salem Gastroenterology Consultants and Salem Hospital, Salem, OR

- 2002 – present | Clinical Assistant Professor of Medicine, Oregon Health and Science University, Portland, OR
Hospital Affiliations
- July 2002 – present | Active Medical Staff, Salem Hospital, Salem, Oregon
- 1993 – 2002 | University of Kentucky Chandler Medical Center
- Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Lexington, Kentucky
- Department of Veterans Affairs Medical Center Department of Internal Medicine, Division of Gastroenterology, Lexington, Kentucky
Honors & Awards
- 1971 | Eagle Scout
- 1982 | Phi Kappa Phi
- 1986 | Alpha Omega Alpha
- 1991 | Glaxo Fellow’s Award
- 1993 | Physician Scientist Award, University of Kentucky
- 1990 – 1999 | A.M.A. Physician’s Recognition Award
Licensure & Certification
- North Carolina Medical License no. 32109 issued 1/23/88 (inactive)
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Minnesota Medical License no. 333939 issued 3/10/90 (inactive)

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Kentucky Medical License no. 29513 issued 6/18/93

- Utah Medical License no. 4826413-1205 issued 11/13/0
- Oregon Medical License no. MD23505 issued 1/18/02
- National Board of Medical Examiners, certificate no. 310525 issued 7/1/87
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American Board of Internal Medicine, certificate no. 124312 issued 9/13/89

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American Board of Internal Medicine, Gastroenterology, certificate no. 124312 Issued 11/93, renewed 2002, with expiration 11/2013

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National Board of Nutrition Support Certification, Certified Nutrition Support Physician Issued 10/20/04, with expiration 10/20/09

Professional Societies
- Phi Kappa Phi
- American College of Physicians - Elected FACP January 1996
- Alpha Omega Alpha
- American Gastroenterological Association - Elected AGAF May 2006
- American College of Gastroenterology - Elected FACG February 1998
- American Pancreatic Association
- Sigma Xi
- American Society for Gastrointestinal Endoscopy
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American College of Nutrition - Elected FACN October 2003

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American Society for Parenteral and Enteral Nutrition

- Oregon Medical Association
- Marion-Polk Medical Society
Publications - Peer Reviewed Journals
(Dr. Gates has authored or co-authored a total of 39 scientific and clinical research papers, invited reviews, and textbook chapters. A representative sampling is listed below.)
- U.G. Klueppelberg, L.K. Gates, F.S. Gorelick, L.J. Miller. Agonist-regulated Phosphorylation of the Pancreatic Cholecystokinin Receptor. J. Biol. Chem. Feb. 1991 266(4):2403-8
- L.J. Miller, E.M. Hadac, L.K. Gates, H.Y. Gaisano. Binding of a Phenethyl Ester Analogue of Cholecystokinin to the Solubilized Pancreatic Cholecystokinin Receptor: Use in Ligand-Affinity Chromatography. B B R C Mar 1992 183(2):396-404
- L.K. Gates, C.D. Ulrich, L.J. Miller. Multiple Kinases Phosphorylate the Pancreatic Cholecystokinin Receptor in an Agonist Dependent Manner. A J P June 1993 264(Gastrointest. Liver Physiol. 27):G840-847
- M.P. Lutz, D.I. Pinon, L.K. Gates, S. Shenolikar, L.J. Miller.Control of Cholecystokinin Receptor Dephosphorylation in Pancreatic Acinar Cells  J. Biol. Chem. June 1993 268(16):12136-12142
- C.D. Ulrich, D.I. Pinon, E.M. Hadac, E.L. Holicky, A. Chang-Miller, L.K. Gates, L.J. Miller. Intrinsic Photoaffinity Labeling of Native and Recombinant Rat Pancreatic Secretin Receptors.   Gastroenterology Nov. 1993 105(5):1534-1543
- Z. Zhu, M. Lutz, L.K. Gates, L.J. Miller.Mechanisms of Heterologous Agonist-Stimulated Phosphorylation of Cholecystokinin Receptor.   A J P Apr. 1994  266(Cellular Physiol):C904-10
- L.K. Gates, R.H. Wiesner, R.A.F. Krom, J. Steers, G.J. Gores, J.E. Hay, M.K. Porayko. The Etiology and Incidence of Unconjugated Hyperbilirubinemia Following Orthotopic Liver Transplantation.   Am J Gastroenterol Sep. 1994 89(9):1541-1543
- L.K. Gates, R.F. Keate, M.A. Gertz, L.J. Burgart."A Patient with Weight Loss, Hypogammaglobulinemia, and Diarrhea" (CPC)  Gastroenterology International Dec. 1994 7(4):172-178
- L.K. Gates, A.J. Cameron, D.M. Nagorney, J.R. Goellner, D.R. Farley. Primary Leiomyosarcoma of the Liver Mimicking Liver Abscess. Am J Gastroenterol Apr. 1995 90(4):649-652
- W.G. Simpson<, L. Marsano, L.K. Gates. Enteral Nutritional Support in Acute Alcoholic Pancreatitis.  J Am Col Nutrition Jun. 1995 14(6):662-665
- J.D. Tooson, L.S. Marsano, L.K. Gates.  Pediatric Rectal Dieulafoy's Lesion.  Am J Gastroenterol Dec. 1995 90(12):2232-2233
- D.C. Whitcomb, R.A. Preston, C.E. Aston, M.J. Sossenheimer, P.S. Barua, Y.Z. Zhang, A. Wong-Chong, G.J. White, P.G. Wood, L.K. Gates, C.D. Ulrich, S.P. Martin, J.C. Post, G.D. Erlich.  A Gene for Hereditary Pancreatitis Maps to Chromosome 7q35.  Gastroenterology June 1996 110(6):1975-1980
- D.A. McMenamin, L.K. Gates.  Retrospective Analysis of the Effect of Contrast Enhanced CT on the Outcome of Acute Pancreatitis.  Am J Gastroenterol July 1996 91(7):1384-1387
- D.Y. Kortas, L.K. Gates.  Vertebral Osteomyelitis Mimicking Chronic Pancreatitis. Digestive Diseases and Sciences July 1996 41(7):1527-1529
- J.D. Tooson, L.K. Gates.  Bowel Preparation before Colonoscopy. Postgraduate Medicine Aug. 1996 100(2):203-214
- L.K. Gates, R.F. Keate, J.J. Smalley, Jr., J.D. Richardson.  Macrodactylia Fibrolipomatosis Complicated by Multiple Small Intestinal Lipomas and Intussusception. Clinical Gastroenterology Sept. 1996 23(3):241-242
- D.C. Whitcomb, M.C. Gorry, R.A. Preston, W. Furey, M.J. Sossenheimer, C.D. Ulrich, S.P. Martin, L.K. Gates, S.T. Amann, P.P. Toskes, R. Liddle, K. McGrath, G. Uomo, J.C. Post, G.D. Ehrlich. Hereditary Pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nature Genetics Oct. 1996 14(2):141-145
- A.B. Lowenfels, P. Maisonneuve, E.P. DiMagno, Y. Elitsur, L.K. Gates, J. Perrault, D.C. Whitcomb, and the International Hereditary Pancreatitis Study Group.  Hereditary Pancreatitis and the Risk of Pancreatic Cancer. J National Cancer Institute Mar. 1997 89(6):442-446
- L.K. Gates.  AMA Negative Immunocholangitis and Chronic Pancreatitis, a Case Report.  Pancreas Apr. 1997 14(3):311-313
- M.J. Sossenheimer, C.E. Aston, R.A. Preston, L.K. Gates, C.D. Ulrich, S.P. Martin, Y. Zhang, M.C. Gorry, G.D. Ehrlich, and D.C. Whitcomb.  Clinical Characteristics of Hereditary Pancreatitis in a Large Family Based on High-Risk Haplotype.  Am J Gastroenterol July 1997 92(7):1113-1116
- M.C. Gorry, D. Gabbaizedeh, W. Furey, L.K. Gates, R.A. Preston, C.E. Aston, Y. Zhang, C. Ulrich, G.D. Ehrlich, and D.C. Whitcomb.   Mutations in the Cationic Trypsinogen Gene are Associated with Recurrent Acute and Chronic Pancreatitis.  Gastroenterology Oct. 1997 113(4):1063-1068
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T.E. Meister, G.W. Varilek, L.S. Marsano, L.K. Gates, Y. Al-Tawil, W.J.S. de Villers.  Endoscopic Management of Rectal Dieulafoy's Lesions:  A Case Series and Review of the Literature. Gastro. Endo. Sept. 1998 48(3):302-305

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G.A. Bracher, A.P. Manocha, J.R. DeBanto, L.K. Gates, A. Slivka, D.C. Whitcomb, B.L. Bleau, C.D. Ulrich, S.P. Martin. Pancreatic Duct Stenting to Treat Pancreatic Ascites.  Gastro Endo June 1999 49(6):710-715

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J.A. Blanchard II, S. Barve, S. Joshi-Barve, R. Talwalker, L.K. Gates. Cytokine Production by CAPAN-1 and CAPAN-2 Cell Lines. Dig Dis Sci May 2000; 45(5):927-32

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F. Fortunato, L.K. Gates. Chronic Alcohol Feeding and Lipopolysaccharide Modulate Apoptotic Effectors in the Rat Pancreas In Vivo.  Pancreas June 2000; 21(2):174-180

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S.T. Amann, L.K. Gates, C.E. Aston, A.Pandya, D.C. Whitcomb. Expression and Penetrance of the Hereditary Pancreatitis Phenotype in Monozygotic Twins.  Gut April 2001; 48:543-8

- Applebaum-Shapiro SE, Finch R, Pfutzer RH, Hepp LA, Gates L, Amann S, Martin S, Ulrich CD 2nd, Whitcomb DC.  Hereditary pancreatitis in North America:  the Pittsburgh-Midwest Multi-Center Pancreatic Study Group Study. 
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D.Y. Kortas, L.S. Haas, W.G. Simpson, N.J. Nickl, L.K. Gates. Mallory-Weiss Tear: A Retrospective Analysis of Predisposing Factors and Predictors of a Complicated Course. Am J Gastroenterol Oct. 2001; 96:2863-2865

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J.A. Blanchard II, S. Barve, S. Joshi-Barve, R. Talwalker, L.K. Gates, Jr. Antioxidants Inhibit Cytokine Production and Suppress NFκB Activation in CAPAN-1 and CAPAN-2 Cell Lines. Dig Dis Sci Dec. 2001; 46:2768-2722

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L.K. Gates, D.V. Holiday.  A Syndrome of Autosomal Dominant Pancreatic Cancer and Multiple Cysts of the Liver and Kidneys.  Gastroenterology Mar. 2002; 122:796-799

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L.S. Haas, L.K. Gates. The Ascites to Serum Amylase Ratio: A Predictor of Mortality in Acute Pancreatitis with Ascites.  Pancreatology May 2002; 2:100-103

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J.R. DeBanto, P.S. Goday, M.R.A. Pedroso, R. Iftikhar, A. Fazel, S. Nayyar, D.L. Conwell, M.T. DeMeo, F.R. Burton, D.C. Whitcomb, C.D. Ulrich II, L.K. Gates, Jr.  Acute Pancreatitis in Children.  Am J Gastroenterol Jul. 2002; 97:1726-1731

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F. Fortunato, X. Deng, L.K. Gates, C.J. McClain, D. Bimmler, R. Graf, D.C. Whitcomb.  Pancreatic Response to Endotoxin after Chronic Alcohol Exposure: Switch from Apoptosis to Necrosis?  Am J Physiol Gastrointest Liver Physiol.  June 2005;

Publications - Invited Reviews
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L.K. Gates  Prophylaxis for ERCP Induced Pancreatitis: Are We There Yet?   Advances in Gastroenterology, Hepatology, and Clinical Nutrition Dec. 1998; 3:340-342

- L.K. Gates Severity Scoring for Acute Pancreatitis: Where do We Stand in 1999?  Current Gastroenterology Reports Apr 1999; 1:134-138
- L.K. Gates, C.D. Ulrich, D.C. Whitcomb.  Hereditary Pancreatitis: Gene Defects and Their Implications.  Surgical Clinics of North America August 1999; 79(4):711-722
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L.K. Gates, Hereditary Pancreatitis.  Current Treatment Options in Gastroenterology August 1999; 2(4):

- L.K. Gates, Hereditary Pancreatitis: Preventive Strategies and Therapeutic Options.  Medical Clinics of North America May 2000; 84(3):589-595
Publications - Book Chapters
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N.J. Nickl, L.K. Gates. Miscelaneous Disorders of the Pancreas.  in Gastrointestinal Endoscopy: An Endoscopic Approach to Gastrointestinal Disease. A.J. Marino, S.B. Benjamin eds.  Blackwell Science, Cambridge, MA

Dr. Gates is married to Jennifer Jensen Gates, and has two daughters, Gwyneth and Vivian.